An Italian research group has developed a diagnostic kit for the detection of “responders” to biologic drugs for rheumatoid arthritis. They are looking for research collaborations with companies that produce pharmacogenomic and companion diagnostic tests. A regional grant can support the co-development of the research results by paying the costs of one year research fellowship.
An Italian research grupo has developed a personalized therapy for rheumatoid arthritis. Recently, some biologic drugs with high potential in controlling the effects of rheumatoid arthritis have been developed. Such drugs have high costs and are not effective on the entire rheumatoid arthritis patients population. Therefore, the development of strategies to predict the clinical response to such drugs is needed, in order to select rapidly and on a large scale those patients who will benefit from the therapy. The proposed technology consists of an innovative kit for the identification of “responders” to the new biologic drugs for the treatment of rheumatoid arthritis.
They are looking for research collaboration with companies involved in the development and commercialization of pharmacogenomic and companion diagnostic tests to co-develop the research results.
This diagnostic kit will integrate gene expression analysis with procedures that allow enriching of the cell types responsible for the production of inflammatory molecules, thus providing a test with a greater predictive power than the basic whole blood analysis.
Deadline of the call: 30/08/2017
Deadline for EoIs: 15/07/2017
- Specific area of activity of the partner: Type: companies involved in the development and commercialization of pharmacogenomic and companion diagnostic tests.
Role: co-development of the research results.
A pharmacogenetics tool for rheumatoid arthritis biologic drugs will not only help to select patients that would definitely benefit from the drug, but will also assist in revealing the right dose for individual patients, saving a lot of money for the healthcare system. Furthermore, the ability to assess an individual's reaction to a drug before it is prescribed will increase a physician's confidence in prescribing the drug and the patient's confidence in taking the drug itself.
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