An Italian company with high experience in production and purification of API (Active Pharmaceutical Ingredient) develops a fermentation process to produce a proprietary small molecule. An experienced researcher with transcriptomics and metabolomics know how is sought within Society & Enterprise Panel of Individual Fellowships of Marie- Sklodowska-Curie Actions. He/she should contribute to further optimize the production process as well as enhance the knowledge of microbial biochemical pathways.
The Italian company has several years of experience in the identification, development and production of high quality active principles, for use in the pharmaceutical and health food field. The company has also a strong experience in the production of APIs that require high containment as well as fermentation-origin APIs.
The multipurpose fermentation suite allows the company to develop several production processes to obtain API for the Pharma market. One of this regards the production of a small molecule by using an unconventional bacterium. Since the yield remains very low, one of the most important objective is to clarify the biochemical pathway that leads to final product in order to optimize the entire production process.
For this purpose the company would like to hire an omics data analyst with a PhD or an experienced researcher (scientific worker) with several years of research experience in bioinformatics analysis or related disciplines in the framework of EU program Fellowships: MSCA-IF-EF-SE.
The candidate should contribute to the further design and development of the transcriptomics and metabolomics experiments as well as enhancements of the intuitive user experience and data exploration. He/she should also focus on fermentation process.
The anticipated duration of the project is 2 years. The deadline of the call is 9th September 2020. The deadline for EoIs is 30 July 2020.
- Specific area of activity of the partner: The purpose of the partnership is a common application for funding under the EU program MSCA-IF-EF-SE Society and Enterprise panel, where the Italian company will be the hosting organisation for the researcher.
The candidate should contribute to further design and development of omics experiment as well omics data analysis in order to clarify the biochemical pathway for the production of the molecule of interest.
He/she should also focus on fermentation process applying its experience of comparative metabolomics analysis.
Working with external partner the candidate will also develop his /her knowledge using the latest next generation sequencing technology and will gather experience in de-novo genome sequencing of unconventional bacterium.
The scientific researcher should have a bioinformatics background and have experience in most of the following areas:
- Plan and execution of metabolomics and transcriptomics experiment
- omics data analysis
- Illumina technology for NGS analysis
- Metabolic flux analysis
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