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RDHU20200811001

H2020-EIC-FTI: Hungarian SME is looking for manufacturing/trading company of laboratory equipment or medical devices, and an academic research group with outstanding scientific excellence in extracellular vesicles research.

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ABSTRACT

A Hungarian biotechnology R&D company is developing a novel platform for isolation of extracellular vesicles from biofluids. The device enables high-quality, scalable, and cost-efficient isolation from any biofluid. The company seeks partners to develop the platform to a market-ready device in the H2020 EIC-FTI call. Partners needed: (1) manufacturing company with strong market position and distribution network, (2) university research group with experience in extracellular vesicles research.


FULL DESCRIPTION

Exosomes are small, cell-derived lipid vesicles that play key roles in intercellular communication. Despite their outstanding potential in diagnostic and therapeutic use, the transition of exosome-based applications from laboratory research to clinical practice is hindered by the lack of a gold standard, optimal technology for the isolation of exosomes from bodily fluids. The novel platform provides the solution to the above problem. It is a highly effective isolation platform for exosomes, with high throughput, good reproducibility, decreasing the required effort and time for isolation. The innovative platform is essentially scalable, has low initial costs, and requires minimal experience from the user. Therefore, its widespread use will decrease the barriers for exosome-based applications. The aim is to provide a special equipment, customised consumables, and methodology to the specific needs in exosome isolation from different biofluids, such as blood or urine.

The coordinator of the planned project is a Hungarian biotechnology R&D company developing novel in-house R&D projects and providing innovative preclinical and clinical R&D services since 2003. The company is a worldwide R&D service provider with opinion leader scientific management. As technological development of the device has reached the prototype stage, the coordinator company is now preparing for further development in a Fast Track to Innovation project.

The planned project will build upon the SME Instrument Phase 1 project recently carried out by the coordinator company. The deadline for the targeted call (EIC-FTI) is 27 October 2020.
The project will be carried out by a small consortia of 3 to 5 partners.

Partners sought:
- manufacturing company with strong market position and distribution network. Tasks: manufacturing of the novel extracellular vesicles isolation platform
- academic research group with outstanding scientific excellence in extracellular vesicles research. Tasks: isolation of targeted, specific sub-population of extracellular vesicles

Deadline for EOIs: 30 September 2020.


Partner expertise sought:

- Specific area of activity of the partner: Partner 1
- Type of partner sought: Industry
- Specific area of activity of the partner: Commercial production and/or distribution of laboratory equipment and/or medical devices, In Vitro Diagnostics
- Task to be performed: During the project the partnerís tasks will include contribution to the requirements specification; manufacturing of the novel extracellular vesicles isolation platform; and contribution to dissemination and exploitation activities aiding future commercialization.
After the project, the partner would be involved in the commercialization of the project results, providing the novel extracellular vesicles isolation platform to be used by research laboratories.

Partner 2
- Type of partner sought: Academic Research Group
- Specific area of activity of the partner: Isolation of targeted, specific sub-population of extracellular vesicles as well as validation of performance of the isolation platform.
- Task to be performed: testing the novel extracellular vesicles isolation platform in their everyday laboratory practice by isolation of targeted, specific sub-population of extracellular vesicles.


Advantages & innovations:

The novel platform enables high-quality, scalable, and cost-efficient isolation of extracellular vesicles from all types of biofluids. The novel chromatography platform specifically tailored for the isolation of exosomes from biofluids combines size exclusion chromatography (SEC) and immune affinity chromatography (IAC). The platform has a user-friendly and modularly expandable control platform that supports multi-channel operation. Ready-to-use SEC and IAC columns are available as customized consumables.

As a first minimum viable product the novel platform can be developed as a laboratory equipment for the life science research market. Extracellular vesicles is a booming research field based on the dramatically increasing number of scientific publications with an immediate need for a high-quality, scalable, and cost-efficient isolation platform. Growth drivers include cancer diagnosis and treatment as well as advanced applications of exosomes for e.g. drug delivery.

The platform has the potential to be further developed for clinical use as an In Vitro Diagnostic (IVD) and/or for therapeutic use as well.


Development Stage:

Prototype available for demonstration

Programme - Call:

Evaluation scheme: continuous submission scheme

Website: https://ec.europa.eu/programmes/horizon2020/en/h2020-section/fast-track-innovation-pilot

Deadline: 27/10/2020

Coordinator required: No

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KEY INFORMATION

Country of origin
HUNGARY
Profile date
13/08/2020
Deadline
30/09/2020

PARTNERSHIP(S) SOUGHT

Research cooperation agreement

CLASSIFICATIONS

INDUSTRY SECTORS
Information Processing & Systems \ Life Sciences \ Biosciences and Health \ Drug Discovery and Drug Development \ Diagnostics \ Medical Devices
TECHNOLOGY KEYWORDS
ELECTRONICS, IT AND TELECOMMS / Electronic circuits, components and equipment / Electronic engineering / BIOLOGICAL SCIENCES / Medicine, Human Health / Diagnostics, Diagnosis / BIOLOGICAL SCIENCES / Medicine, Human Health / Medical Research / BIOLOGICAL SCIENCES / Medicine, Human Health / Medical Technology / Biomedical Engineering / BIOLOGICAL SCIENCES / Biology / Biotechnology / In vitro Testing, Trials
COMMERCIAL KEYWORDS
none...
MARKET KEYWORDS
MEDICAL/HEALTH RELATED / Diagnostic / Diagnostic services / MEDICAL/HEALTH RELATED / Diagnostic / In-vitro diagnostics / MEDICAL/HEALTH RELATED / Medical equipment / Laboratory equipment / MEDICAL/HEALTH RELATED / Medical equipment / Diagnostic equipment

FIND OUT MORE

Contact Enterprise Europe Network Scotland by email at info@enterprise-europe-scotland.com, quoting reference number RDHU20200811001